Hepatitis C vaccine

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Hepatitis C Virus and Vaccine Development

The prevalence of Hepatitis C virus (HCV) is approximately 3% around the world. This virus causes chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The effectiveness of interferon-α and ribavirin therapy is about 50% and is associated with significant toxicity and cost. Hence, generating new vaccines or drugs is an obligation. However, there is no vaccine available for clinical u...

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Polymer-basednanoadjuvants for hepatitis C vaccine: The perspectives of immunologists

The hepatitis C virus (HCV) is an infection that affects the liver tissues in humans, leading to the development of effective prophylactic and therapeutic HCV vaccines to prevent a global epidemic. Scientists consider it challenging to produce a therapeutic vaccine for the treatment of hepatocellular carcinoma as opposed to a preventative vaccine. However, several drawbacks are involved with a ...

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Hepatitis C Virus and Vaccine Development

The prevalence of Hepatitis C virus (HCV) is approximately 3% around the world. This virus causes chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The effectiveness of interferon-α and ribavirin therapy is about 50% and is associated with significant toxicity and cost. Hence, generating new vaccines or drugs is an obligation. However, there is no vaccine available for clinical u...

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Hepatitis C vaccine approaches phase II trial.

The fi rst prophylactic hepatitis C vaccine to reach human trials could enter phase II testing this year, a landmark for a fi eld that has faced many technical challenges since the virus was identifi ed in 1989. If this vaccine — or one of several other candidates — is successful, the public health impact could be substantial. Hepatitis C is a major cause of liver disease, including hepatocellu...

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hepatitis c virus and vaccine development

the prevalence of hepatitis c virus (hcv) is approximately 3% around the world. this virus causes chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. the effectiveness of interferon-α and ribavirin therapy is about 50% and is associated with significant toxicity and cost. hence, generating new vaccines or drugs is an obligation. however, there is no vaccine available for clinical u...

متن کامل

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ژورنال

عنوان ژورنال: Human Vaccines & Immunotherapeutics

سال: 2014

ISSN: 2164-5515,2164-554X

DOI: 10.4161/hv.29033